Distribution and excretion of the PEGylated recombinant new human interleukin-6 (PEG-rhIL-6) in rats
نویسندگان
چکیده
The distribution and excretion of I-PEG-rhIL-6 in rats were investigated by I isotope tracing method. Results showed that the concentration in the brain is lowest and highest in plasma 8 h post-injection. The results indicated that the blood was the main site of action of I-PEG-rhIL-6, which provides a basis for PEG-rhIL-6 treating of thrombocytopenia.
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Cloning and Expression of Recombinant Human Interleukin-7 in Chinese Hamster Ovary (CHO) Cells
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